CSBC Supported Publications

Publications

  • 2018 September 13 |

    HIF signaling in osteoblast-lineage cells promotes systemic breast cancer growth and metastasis in mice..

    Devignes CS, Aslan Y, Brenot A, Devillers A, Schepers K, Fabre S, Chou J, Casbon AJ, Werb Z, Provot S. Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):E992-E1001. doi: 10.1073/pnas.1718009115. Epub 2018 Jan 16.  Read more
  • 2018 September 13 |

    Comparing side chain packing in soluble proteins, protein-protein interfaces, and transmembrane proteins.Gaines JC, Acebes S, Virrueta A, Butler M, Regan L, O’Hern CS Proteins. 2018 May;86(5):581-591. doi: 10.1002/prot.25479. Epub 2018 Feb 26..

    Gaines JC, Acebes S, Virrueta A, Butler M, Regan L, O'Hern CS Proteins. 2018 May;86(5):581-591. doi: 10.1002/prot.25479. Epub 2018 Feb 26.  Read more
  • 2018 September 13 |

    Single-Cell RNA-seq Reveals a Subpopulation of Prostate Cancer Cells with Enhanced Cell-Cycle-Related Transcription and Attenuated Androgen Response..

    Horning AM, Wang Y, Lin CK, Louie AD, Jadhav RR, Hung CN, Wang CM, Lin CL, Kirma NB, Liss MA, Kumar AP, Sun L, Liu Z, Chao WT, Wang Q, Jin VX, Chen CL, Huang TH Cancer Res. 2018 Feb 15;78(4):853-864. doi: 10.1158/0008-5472.CAN-17-1924. Epub 2017 Dec 12.  Read more
  • 2018 September 13 |

    Tamoxifen Resistance in Breast Cancer Is Regulated by the EZH2-ERα-GREB1 Transcriptional Axis.

    Wu Y, Zhang Z, Cenciarini ME, Proietti CJ, Amasino M, Hong T, Yang M, Liao Y, Chiang HC, Kaklamani VG, Jeselsohn R6, Vadlamudi RK, Huang TH, Li R, De Angelis C, Fu X, Elizalde PV, Schiff R, Brown M, Xu. Cancer Res. 2018 Feb 1;78(3):671-684. doi: 10.1158/0008-5472.CAN-17-1327. Epub 2017 Dec 6  Read more
  • 2018 September 13 |

    Targeting minimal residual disease: a path to cure?.

    Luskin MR, Murakami MA, Manalis SR, Weinstock DM. Nat Rev Cancer. 2018 Apr;18(4):255-263. doi: 10.1038/nrc.2017.125. Epub 2018 Jan 29.  Read more
  • 2018 June 11 |

    Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types..

    Mead, BE, Ordovas-Montanes, J, Braun, AP, Levy, LE, Bhargava, P, Szucs, MJ et al.. BMC Biol. 2018;16 (1):62. doi: 10.1186/s12915-018-0527-2  Read more
  • 2018 June 05 |

    Scarless genome editing: progress towards understanding genotype-phenotype relationships..

    Elison, GL, Acar, M. Curr. Genet. 2018; :. doi: 10.1007/s00294-018-0850-8  Read more
  • 2018 June 01 |

    Combination Approach for Detecting Different Types of Alterations in Circulating Tumor DNA in Leiomyosarcoma.

    Przybyl, J, Chabon, JJ, Spans, L, Ganjoo, KN, Vennam, S, Newman, AM et al.. Clin. Cancer Res. 2018;24 (11):2688-2699. doi: 10.1158/1078-0432.CCR-17-3704  Read more
  • 2018 May 30 |

    Mechanisms for the epigenetic inheritance of stress response in single cells..

    Xue, Y, Acar, M. Curr. Genet. 2018; :. doi: 10.1007/s00294-018-0849-1  Read more
  • 2018 May 18 |

    The number of titrated microRNA species dictates ceRNA regulation.

    Chiu, HS, Martínez, MR, Komissarova, EV, Llobet-Navas, D, Bansal, M, Paull, EO et al.. Nucleic Acids Res. 2018;46 (9):4354-4369. doi: 10.1093/nar/gky286  Read more
  • 2018 May 17 |

    Molecular subtyping of colorectal cancer: Recent progress, new challenges and emerging opportunities.

    Wang, W, Kandimalla, R, Huang, H, Zhu, L, Li, Y, Gao, F et al.. Semin. Cancer Biol. 2018; :. doi: 10.1016/j.semcancer.2018.05.002  Read more
  • 2018 May 15 |

    Programmable sequential mutagenesis by inducible Cpf1 crRNA array inversion..

    Chow, RD, Kim, HR, Chen, S. Nat Commun. 2018;9 (1):1903. doi: 10.1038/s41467-018-04158-z  Read more
  • 2018 May 14 |

    GFPT2-expressing cancer-associated fibroblasts mediate metabolic reprogramming in human lung adenocarcinoma..

    Zhang, W, Bouchard, G, Yu, A, Shafiq, M, Jamali, M, Shrager, JB et al.. Cancer Res. 2018; :. doi: 10.1158/0008-5472.CAN-17-2928  Read more
  • 2018 May 11 |

    Profiling Tumor Infiltrating Immune Cells with CIBERSORT.

    Chen, B, Khodadoust, MS, Liu, CL, Newman, AM, Alizadeh, AA. Methods Mol. Biol. 2018;1711 :243-259. doi: 10.1007/978-1-4939-7493-1_12  Read more
  • 2018 May 09 |

    Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.

    Waszak, SM, Northcott, PA, Buchhalter, I, Robinson, GW, Sutter, C, Groebner, S et al.. Lancet Oncol. 2018; :. doi: 10.1016/S1470-2045(18)30242-0  Read more
  • 2018 May 08 |

    Stability of Control Networks in Autonomous Homeostatic Regulation of Stem Cell Lineages.

    Komarova, NL, van den Driessche, P. Bull. Math. Biol. 2018;80 (5):1345-1365. doi: 10.1007/s11538-017-0283-4  Read more
  • 2018 May 08 |

    Comparing side chain packing in soluble proteins, protein-protein interfaces, and transmembrane proteins.

    Gaines, JC, Acebes, S, Virrueta, A, Butler, M, Regan, L, O'Hern, CS et al.. Proteins. 2018;86 (5):581-591. doi: 10.1002/prot.25479  Read more
  • 2018 May 08 |

    Cross-Cohort Analysis Identifies a TEAD4-MYCN Positive Feedback Loop as the Core Regulatory Element of High-Risk Neuroblastoma.

    Rajbhandari, P, Lopez, G, Capdevila, C, Salvatori, B, Yu, J, Rodriguez-Barrueco, R et al.. Cancer Discov. 2018;8 (5):582-599. doi: 10.1158/2159-8290.CD-16-0861  Read more
  • 2018 May 01 |

    DRUG-NEM: Optimizing drug combinations using single-cell perturbation response to account for intratumoral heterogeneity.

    Anchang, B, Davis, KL, Fienberg, HG, Williamson, BD, Bendall, SC, Karacosta, LG et al.. Proc. Natl. Acad. Sci. U.S.A. 2018;115 (18):E4294-E4303. doi: 10.1073/pnas.1711365115  Read more
  • 2018 April 25 |

    Systematic Evaluation of Molecular Networks for Discovery of Disease Genes.

    Huang, JK, Carlin, DE, Yu, MK, Zhang, W, Kreisberg, JF, Tamayo, P et al.. Cell Syst. 2018;6 (4):484-495.e5. doi: 10.1016/j.cels.2018.03.001  Read more
  • 2018 April 18 |

    Heritable stress response dynamics revealed by single-cell genealogy.

    Chatterjee, M, Acar, M. Sci Adv. 2018;4 (4):e1701775. doi: 10.1126/sciadv.1701775  Read more
  • 2018 April 17 |

    The Immune Landscape of Cancer.

    Thorsson, V, Gibbs, DL, Brown, SD, Wolf, D, Bortone, DS, Ou Yang, TH et al.. Immunity. 2018;48 (4):812-830.e14. doi: 10.1016/j.immuni.2018.03.023  Read more
  • 2018 April 16 |

    BET Proteins Exhibit Transcriptional and Functional Opposition in the Epithelial-to-Mesenchymal Transition.

    Andrieu, GP, Denis, GV. Mol. Cancer Res. 2018;16 (4):580-586. doi: 10.1158/1541-7786.MCR-17-0568  Read more
  • 2018 April 16 |

    Quantitative assessment of protein activity in orphan tissues and single cells using the metaVIPER algorithm.

    Ding, H, Douglass, EF Jr, Sonabend, AM, Mela, A, Bose, S, Gonzalez, C et al.. Nat Commun. 2018;9 (1):1471. doi: 10.1038/s41467-018-03843-3  Read more
  • 2018 April 05 |

    A global transcriptional network connecting noncoding mutations to changes in tumor gene expression.

    Zhang, W, Bojorquez-Gomez, A, Velez, DO, Xu, G, Sanchez, KS, Shen, JP et al.. Nat. Genet. 2018;50 (4):613-620. doi: 10.1038/s41588-018-0091-2  Read more
  • 2018 April 05 |

    A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development.

    Cesana, M, Guo, MH, Cacchiarelli, D, Wahlster, L, Barragan, J, Doulatov, S et al.. Cell Stem Cell. 2018;22 (4):575-588.e7. doi: 10.1016/j.stem.2018.03.012  Read more
  • 2018 March 30 |

    Cancer CRISPR Screens In Vivo..

    Chow, RD, Chen, S. Trends Cancer. 2018;4 (5):349-358. doi: 10.1016/j.trecan.2018.03.00  Read more
  • 2018 March 29 |

    Integrative analysis reveals functional and regulatory roles of H3K79me2 in mediating alternative splicing..

    Li, T, Liu, Q, Garza, N, Kornblau, S, Jin, VX. Genome Med. 2018;10 (1):30. doi: 10.1186/s13073-018-0538-1  Read more
  • 2018 March 28 |

    Microenvironment-Mediated Mechanisms of Resistance to HER2 Inhibitors Differ between HER2+ Breast Cancer Subtypes.

    Watson, SS, Dane, M, Chin, K, Tatarova, Z, Liu, M, Liby, T et al.. Cell Syst. 2018;6 (3):329-342.e6. doi: 10.1016/j.cels.2018.02.001  Read more
  • 2018 March 28 |

    Automated brightfield morphometry of 3D organoid populations by OrganoSeg.

    Borten, MA, Bajikar, SS, Sasaki, N, Clevers, H, Janes, KA. Sci Rep. 2018;8 (1):5319. doi: 10.1038/s41598-017-18815-8  Read more
  • 2018 March 22 |

    iterClust: a statistical framework for iterative clustering analysis.

    Ding, H, Wang, W, Califano, A. Bioinformatics. 2018; :. doi: 10.1093/bioinformatics/bty176  Read more
  • 2018 March 15 |

    A MicroRNA Signature Associated With Metastasis of T1 Colorectal Cancers to Lymph Nodes.

    Ozawa, T, Kandimalla, R, Gao, F, Nozawa, H, Hata, K, Nagata, H et al.. Gastroenterology. 2018;154 (4):844-848.e7. doi: 10.1053/j.gastro.2017.11.275  Read more
  • 2018 March 11 |

    Brain cancer genomics and epigenomics..

    Archer, TC, Sengupta, S, Pomeroy, SL. Handb Clin Neurol. 2018;148 :785-797. doi: 10.1016/B978-0-444-64076-5.00050-8  Read more
  • 2018 March 07 |

    Genome-wide discovery and identification of a novel miRNA signature for recurrence prediction in stage II and III colorectal cancer.

    Kandimalla, R, Gao, F, Matsuyama, T, Ishikawa, T, Uetake, H, Takahashi, N et al.. Clin. Cancer Res. 2018; :. doi: 10.1158/1078-0432.CCR-17-3236  Read more
  • 2018 March 01 |

    T-Cell Immunopeptidomes Reveal Cell Subtype Surface Markers Derived From Intracellular Proteins.

    Olsson, N, Schultz, LM, Zhang, L, Khodadoust, MS, Narayan, R, Czerwinski, DK et al.. Proteomics. 2018; :e1700410. doi: 10.1002/pmic.201700410  Read more
  • 2018 March 01 |

    BET proteins in abnormal metabolism, inflammation, and the breast cancer microenvironment..

    Andrieu, GP, Shafran, JS, Deeney, JT, Bharadwaj, KR, Rangarajan, A, Denis, GV et al.. J. Leukoc. Biol. 2018; :. doi: 10.1002/JLB.5RI0917-380RR  Read more
  • 2018 February 20 |

    Oligomeric proanthocyanidins (OPCs) target cancer stem-like cells and suppress tumor organoid formation in colorectal cancer.

    Toden, S, Ravindranathan, P, Gu, J, Cardenas, J, Yuchang, M, Goel, A et al.. Sci Rep. 2018;8 (1):3335. doi: 10.1038/s41598-018-21478-8  Read more
  • 2018 February 15 |

    Optimizing homeostatic cell renewal in hierarchical tissues.

    Alvarado, C, Fider, NA, Wearing, HJ, Komarova, NL. PLoS Comput. Biol. 2018;14 (2):e1005967. doi: 10.1371/journal.pcbi.1005967  Read more
  • 2018 February 14 |

    The ABCs of PTMs.

    Barber, KW, Rinehart, J. Nat. Chem. Biol. 2018;14 (3):188-192. doi: 10.1038/nchembio.2572  Read more
  • 2018 February 10 |

    Comprehensive characterisation of compartment-specific long non-coding RNAs associated with pancreatic ductal adenocarcinoma.

    Arnes, L, Liu, Z, Wang, J, Carlo Maurer, H, Sagalovskiy, I, Sanchez-Martin, M et al.. Gut. 2018; :. doi: 10.1136/gutjnl-2017-314353  Read more
  • 2018 February 01 |

    Innate and acquired immune surveillance in the postdissemination phase of metastasis..

    Gonzalez, H, Robles, I, Werb, Z. FEBS J. 2018;285 (4):654-664. doi: 10.1111/febs.14325  Read more
  • 2018 February 01 |

    Cancer-associated fibroblasts regulate endothelial adhesion protein LPP to promote ovarian cancer chemoresistance..

    Leung, CS, Yeung, TL, Yip, KP, Wong, KK, Ho, SY, Mangala, LS et al.. J. Clin. Invest. 2018;128 (2):589-606. doi: 10.1172/JCI95200  Read more
  • 2018 January 30 |

    HIF signaling in osteoblast-lineage cells promotes systemic breast cancer growth and metastasis in mice.

    Devignes, CS, Aslan, Y, Brenot, A, Devillers, A, Schepers, K, Fabre, S et al.. Proc. Natl. Acad. Sci. U.S.A. 2018;115 (5):E992-E1001. doi: 10.1073/pnas.1718009115  Read more
  • 2018 January 16 |

    Functional Genomics Approach Identifies Novel Signaling Regulators of TGFα Ectodomain Shedding.

    Wilson, JL, Kefaloyianni, E, Stopfer, L, Harrison, C, Sabbisetti, VS, Fraenkel, E et al.. Mol. Cancer Res. 2018;16 (1):147-161. doi: 10.1158/1541-7786.MCR-17-0140  Read more
  • 2018 January 12 |

    Accuracy of four mononucleotide-repeat markers for the identification of DNA mismatch-repair deficiency in solid tumors.

    Takehara, Y, Nagasaka, T, Nyuya, A, Haruma, T, Haraga, J, Mori, Y et al.. J Transl Med. 2018;16 (1):5. doi: 10.1186/s12967-017-1376-4  Read more
  • 2018 January 01 |

    SparseIso: a novel Bayesian approach to identify alternatively spliced isoforms from RNA-seq data.

    Shi, X, Wang, X, Wang, TL, Hilakivi-Clarke, L, Clarke, R, Xuan, J et al.. Bioinformatics. 2018;34 (1):56-63. doi: 10.1093/bioinformatics/btx557  Read more
  • 2017 December 29 |

    Single-cell RNA sequencing reveals gene expression signatures of breast cancer-associated endothelial cells.

    Sun, Z, Wang, CY, Lawson, DA, Kwek, S, Velozo, HG, Owyong, M et al.. Oncotarget. 2018;9 (13):10945-10961. doi: 10.18632/oncotarget.23760  Read more
  • 2017 December 20 |

    Dummy: Determining therapeutic susceptibility in multiple myeloma by single-cell mass accumulation ( Drug Resistance, Metastasis, U01).

    Cetin, AE, Stevens, MM, Calistri, NL, Fulciniti, M, Olcum, S, Kimmerling, RJ et al.. Nat Commun. 2017;8 (1):1613. doi: 10.1038/s41467-017-01593-2  Read more
  • 2017 December 19 |

    Development of Novel ImmunoPET Tracers to Image Human PD-1 Checkpoint Expression on Tumor-Infiltrating Lymphocytes in a Humanized Mouse Model.

    Natarajan, A, Mayer, AT, Reeves, RE, Nagamine, CM, Gambhir, SS. Mol Imaging Biol. 2017;19 (6):903-914. doi: 10.1007/s11307-017-1060-3  Read more
  • 2017 December 15 |

    A Panel of Methylated MicroRNA Biomarkers for Identifying High-Risk Patients With Ulcerative Colitis-Associated Colorectal Cancer..

    Toiyama, Y, Okugawa, Y, Tanaka, K, Araki, T, Uchida, K, Hishida, A et al.. Gastroenterology. 2017;153 (6):1634-1646.e8. doi: 10.1053/j.gastro.2017.08.037  Read more
  • 2017 December 12 |

    Dummy: Single-cell RNA-seq reveals a subpopulation of prostate cancer cells with enhanced cell cycle-related transcription and attenuated androgen response (Metastasis, Microenvironment, U54).

    Horning, AM, Wang, Y, Lin, CK, Louie, AD, Jadhav, RR, Hung, CN et al.. Cancer Res. 2017; :. doi: 10.1158/0008-5472.CAN-17-1924  Read more
  • 2017 December 07 |

    Early Detection of Molecular Residual Disease in Localized Lung Cancer by Circulating Tumor DNA Profiling.

    Chaudhuri, AA, Chabon, JJ, Lovejoy, AF, Newman, AM, Stehr, H, Azad, TD et al.. Cancer Discov. 2017;7 (12):1394-1403. doi: 10.1158/2159-8290.CD-17-0716  Read more
  • 2017 December 06 |

    Dummy: Tamoxifen resistance in breast cancer is regulated by the EZH2-ERα-GREB1 transcriptional axis (Tumor-Immune, U01).

    Wu, Y, Zhang, Z, Cenciarini, ME, Proietti, CJ, Amasino, MF, Hong, T et al.. Cancer Res. 2017; :. doi: 10.1158/0008-5472.CAN-17-1327  Read more
  • 2017 December 05 |

    Dummy: Vimentin Is Required for Lung Adenocarcinoma Metastasis via Heterotypic Tumor Cell-Cancer-Associated Fibroblast Interactions during Collective Invasion (Tumor-Immune, U54).

    Richardson, AM, Havel, LS, Koyen, AE, Konen, JM, Shupe, J, Wiles, WG 4th et al.. Clin. Cancer Res. 2018;24 (2):420-432. doi: 10.1158/1078-0432.CCR-17-1776  Read more
  • 2017 December 01 |

    Dummy: A new method for post-translationally labeling proteins in live cells for fluorescence imaging and tracking (All).

    Hinrichsen, M, Lenz, M, Edwards, JM, Miller, OK, Mochrie, SGJ, Swain, PS et al.. Protein Eng. Des. Sel. 2017;30 (12):771-780. doi: 10.1093/protein/gzx059  Read more
  • 2017 December 01 |

    Dummy: Genome-wide prediction of minor-groove electrostatic potential enables biophysical modeling of protein-DNA binding (U54).

    Chiu, TP, Rao, S, Mann, RS, Honig, B, Rohs, R. Nucleic Acids Res. 2017;45 Brachyury-YAP Regulatory Axis Drives Stemness and Growth in Cancer.. Shah, SR, David, JM, Tippens, ND, Mohyeldin, A, Martinez-Gutierrez, JC, Ganaha, S et al.. Cell Rep. 2017;21 (2):495-507. doi: 10.1016/j.celrep.2017.09.057  Read more
  • 2017 November 28 |

    Quantitative, in situ analysis of mRNAs and proteins with subcellular resolution.

    Kwon, S, Chin, K, Nederlof, M, Gray, JW. Sci Rep. 2017;7 (1):16459. doi: 10.1038/s41598-017-16492-1  Read more
  • 2017 November 25 |

    Relationships Among Obesity, Type 2 Diabetes, and Plasma Cytokines in African American Women.

    Denis, GV, Sebastiani, P, Andrieu, G, Tran, AH, Strissel, KJ, Lombardi, FL et al.. Obesity (Silver Spring). 2017;25 (11):1916-1920. doi: 10.1002/oby.21943  Read more
  • 2017 November 20 |

    KLHL6 Is Preferentially Expressed in Germinal Center-Derived B-Cell Lymphomas.

    Kunder, CA, Roncador, G, Advani, RH, Gualco, G, Bacchi, CE, Sabile, JM et al.. Am. J. Clin. Pathol. 2017;148 (6):465-476. doi: 10.1093/ajcp/aqx099  Read more
  • 2017 November 20 |

    Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer..

    Bajikar, SS, Wang, CC, Borten, MA, Pereira, EJ, Atkins, KA, Janes, KA et al.. Dev. Cell. 2017;43 (4):418-435.e13. doi: 10.1016/j.devcel.2017.10.027  Read more
  • 2017 November 15 |

    Type II Diabetes and Incidence of Estrogen Receptor Negative Breast Cancer in African American Women.

    Palmer, JR, Castro-Webb, N, Bertrand, K, Bethea, TN, Denis, GV. Cancer Res. 2017;77 (22):6462-6469. doi: 10.1158/0008-5472.CAN-17-1903  Read more
  • 2017 November 09 |

    Anti-miR-17 therapy delays tumorigenesis in MYC-driven hepatocellular carcinoma (HCC).

    Dhanasekaran, R, Gabay-Ryan, M, Baylot, V, Lai, I, Mosley, A, Huang, X et al.. Oncotarget. 2018;9 (5):5517-5528. doi: 10.18632/oncotarget.22342  Read more
  • 2017 November 01 |

    Use of Molecular Tools to Identify Patients With Indolent Breast Cancers With Ultralow Risk Over 2 Decades.

    Esserman, LJ, Yau, C, Thompson, CK, van 't Veer, LJ, Borowsky, AD, Hoadley, KA et al.. JAMA Oncol. 2017;3 (11):1503-1510. doi: 10.1001/jamaoncol.2017.1261  Read more
  • 2017 October 27 |

    A confidence building exercise in data and identifiability: Modeling cancer chemotherapy as a case study.

    Eisenberg, MC, Jain, HV. J. Theor. Biol. 2017;431 :63-78. doi: 10.1016/j.jtbi.2017.07.018  Read more
  • 2017 October 22 |

    Combining deep learning and coherent anti-Stokes Raman scattering imaging for automated differential diagnosis of lung cancer.

    Weng, S, Xu, X, Li, J, Wong, STC. J Biomed Opt. 2017;22 (10):1-10. doi: 10.1117/1.JBO.22.10.106017  Read more
  • 2017 October 19 |

    Development of [18F]DASA-23 for Imaging Tumor Glycolysis Through Noninvasive Measurement of Pyruvate Kinase M2..

    Beinat, C, Alam, IS, James, ML, Srinivasan, A, Gambhir, SS. Mol Imaging Biol. 2017;19 (5):665-672. doi: 10.1007/s11307-017-1068-8  Read more
  • 2017 October 16 |

    Identification of a key role of widespread epigenetic drift in Barrett’s esophagus and esophageal adenocarcinoma.

    Luebeck, EG, Curtius, K, Hazelton, WD, Maden, S, Yu, M, Thota, PN et al.. Clin Epigenetics. 2017;9 :113. doi: 10.1186/s13148-017-0409-4  Read more
  • 2017 October 12 |

    Network modeling of kinase inhibitor polypharmacology reveals pathways targeted in chemical screens.

    Ursu, O, Gosline, SJC, Beeharry, N, Fink, L, Bhattacharjee, V, Huang, SC et al.. PLoS ONE. 2017;12 (10):e0185650. doi: 10.1371/journal.pone.0185650  Read more
  • 2017 October 01 |

    Curcumin sensitizes pancreatic cancer cells to gemcitabine by attenuating PRC2 subunit EZH2, and the lncRNA PVT1 expression.

    Yoshida, K, Toden, S, Ravindranathan, P, Han, H, Goel, A. Carcinogenesis. 2017;38 (10):1036-1046. doi: 10.1093/carcin/bgx065  Read more
  • 2017 September 21 |

    Determining the control networks regulating stem cell lineages in colonic crypts..

    Yang, J, Axelrod, DE, Komarova, NL. J. Theor. Biol. 2017;429 :190-203. doi: 10.1016/j.jtbi.2017.06.033  Read more
  • 2017 September 17 |

    Classifying the evolutionary and ecological features of neoplasms.

    Maley, CC, Aktipis, A, Graham, TA, Sottoriva, A, Boddy, AM, Janiszewska, M et al.. Nat. Rev. Cancer. 2017;17 (10):605-619. doi: 10.1038/nrc.2017.69  Read more
  • 2017 September 15 |

    Cost Effectiveness of Screening Patients With Gastroesophageal Reflux Disease for Barrett’s Esophagus With a Minimally Invasive Cell Sampling Device..

    Heberle, CR, Omidvari, AH, Ali, A, Kroep, S, Kong, CY, Inadomi, JM et al.. Clin. Gastroenterol. Hepatol. 2017;15 (9):1397-1404.e7. doi: 10.1016/j.cgh.2017.02.017  Read more
  • 2017 September 12 |

    Effect of cell cycle duration on somatic evolutionary dynamics.

    Wodarz, D, Goel, A, Komarova, NL. Evol Appl. 2017;10 (10):1121-1129. doi: 10.1111/eva.12518  Read more
  • 2017 August 11 |

    Editorial: The Effect of Bias on Estimation of Improved Survival After Diagnosis of Barrett’s Esophagus.

    Zakko, L, Visrodia, K, Wang, KK, Iyer, PG. Am. J. Gastroenterol. 2017;112 (8):1265-1266. doi: 10.1038/ajg.2017.185  Read more
  • 2017 August 02 |

    A Requirement for Mena, an Actin Regulator, in Local mRNA Translation in Developing Neurons.

    Vidaki, M, Drees, F, Saxena, T, Lanslots, E, Taliaferro, MJ, Tatarakis, A et al.. Neuron. 2017;95 (3):608-622.e5. doi: 10.1016/j.neuron.2017.06.048  Read more
  • 2017 July 26 |

    Characterizing Genetic Susceptibility to Breast Cancer in Women of African Ancestry..

    Feng, Y, Rhie, SK, Huo, D, Ruiz-Narvaez, EA, Haddad, SA, Ambrosone, CB et al.. Cancer Epidemiol. Biomarkers Prev. 2017;26 (7):1016-1026. doi: 10.1158/1055-9965.EPI-16-0567  Read more
  • 2017 July 22 |

    High-throughput sequencing for noninvasive disease detection in hematologic malignancies.

    Scherer, F, Kurtz, DM, Diehn, M, Alizadeh, AA. Blood. 2017;130 (4):440-452. doi: 10.1182/blood-2017-03-735639  Read more
  • 2017 July 21 |

    Determining the role of inflammation in the selection of JAK2 mutant cells in myeloproliferative neoplasms.

    Zhang, J, Fleischman, AG, Wodarz, D, Komarova, NL. J. Theor. Biol. 2017;425 :43-52. doi: 10.1016/j.jtbi.2017.05.012  Read more
  • 2017 July 21 |

    PCSF: An R-package for network-based interpretation of high-throughput data..

    Akhmedov, M, Kedaigle, A, Chong, RE, Montemanni, R, Bertoni, F, Fraenkel, E et al.. PLoS Comput. Biol. 2017;13 (7):e1005694. doi: 10.1371/journal.pcbi.1005694  Read more
  • 2017 July 05 |

    Data normalization considerations for digital tumor dissection.

    Newman, AM, Gentles, AJ, Liu, CL, Diehn, M, Alizadeh, AA. Genome Biol. 2017;18 (1):128. doi: 10.1186/s13059-017-1257-4  Read more
  • 2017 June 01 |

    A PET Imaging Strategy to Visualize Activated T Cells in Acute Graft-versus-Host Disease Elicited by Allogenic Hematopoietic Cell Transplant.

    Ronald, JA, Kim, BS, Gowrishankar, G, Namavari, M, Alam, IS, D'Souza, A et al.. Cancer Res. 2017;77 (11):2893-2902. doi: 10.1158/0008-5472.CAN-16-2953  Read more
  • 2017 May 15 |

    A Model-Based Personalized Cancer Screening Strategy for Detecting Early-Stage Tumors Using Blood-Borne Biomarkers..

    Hori, SS, Lutz, AM, Paulmurugan, R, Gambhir, SS. Cancer Res. 2017;77 (10):2570-2584. doi: 10.1158/0008-5472.CAN-16-2904  Read more
  • 2017 May 10 |

    “Obesity-Associated” Breast Cancer in Lean Women: Metabolism and Inflammation as Critical Modifiers of Risk..

    Denis, GV, Palmer, JR. Cancer Prev Res (Phila). 2017;10 (5):267-269. doi: 10.1158/1940-6207.CAPR-17-0083  Read more
  • 2017 April 26 |

    Screening and Preventive Strategies in Esophagogastric Cancer..

    Zakko, L, Lutzke, L, Wang, KK. Surg. Oncol. Clin. N. Am. 2017;26 (2):163-178. doi: 10.1016/j.soc.2016.10.004  Read more
  • 2017 April 25 |

    Oncogene KRAS activates fatty acid synthase, resulting in specific ERK and lipid signatures associated with lung adenocarcinoma.

    Gouw, AM, Eberlin, LS, Margulis, K, Sullivan, DK, Toal, GG, Tong, L et al.. Proc. Natl. Acad. Sci. U.S.A. 2017;114 (17):4300-4305. doi: 10.1073/pnas.1617709114  Read more
  • 2017 April 14 |

    Medulloblastoma: Molecular Classification-Based Personal Therapeutics..

    Archer, TC, Mahoney, EL, Pomeroy, SL. Neurotherapeutics. 2017;14 (2):265-273. doi: 10.1007/s13311-017-0526-y  Read more
  • 2017 April 11 |

    Essential turmeric oils enhance anti-inflammatory efficacy of curcumin in dextran sulfate sodium-induced colitis..

    Toden, S, Theiss, AL, Wang, X, Goel, A. Sci Rep. 2017;7 (1):814. doi: 10.1038/s41598-017-00812-6  Read more
  • 2017 April 03 |

    Methylation of WNT target genes AXIN2 and DKK1 as robust biomarkers for recurrence prediction in stage II colon cancer..

    Kandimalla, R, Linnekamp, JF, van Hooff, S, Castells, A, Llor, X, Andreu, M et al.. Oncogenesis. 2017;6 (4):e308. doi: 10.1038/oncsis.2017.9  Read more
  • 2017 March 30 |

    Antigen presentation profiling reveals recognition of lymphoma immunoglobulin neoantigens..

    Khodadoust, MS, Olsson, N, Wagar, LE, Haabeth, OA, Chen, B, Swaminathan, K et al.. Nature. 2017;543 (7647):723-727. doi: 10.1038/nature21433  Read more
  • 2017 March 13 |

    Parameter estimation for multistage clonal expansion models from cancer incidence data: A practical identifiability analysis..

    Brouwer, AF, Meza, R, Eisenberg, MC. PLoS Comput. Biol. 2017;13 (3):e1005431. doi: 10.1371/journal.pcbi.1005431  Read more
  • 2017 January 11 |

    Acceptability of Human Papillomavirus Self-Sampling for Cervical Cancer Screening in an Indigenous Community in Guatemala.

    Gottschlich, A, Rivera-Andrade, A, Grajeda, E, Alvarez, C, Mendoza Montano, C, Meza, R et al.. J Glob Oncol. 2017;3 (5):444-454. doi: 10.1200/JGO.2016.005629  Read more