Supporting interdisciplinary approaches to cancer research. The CSBC initiative supports research that investigates the challenges of complexity in basic and translational cancer research through the explicit combination of experimental biology and computational modeling, multi-dimensional data analysis, and systems engineering.
Arizona Cancer and Evolution Center
The mission of the Arizona Cancer and Evolution Center (ACE) is to advance our fundamental understanding of cancer and its clinical management through the development and application of evolutionary and ecological models to cancer biology.
An Integrated Systems Approach for Incompletely Penetrant Onco-Phenotypes
We aim to identify key molecular networks upstream of incompletely penetrant phenotypes to better understand the transition from tumor initiation to progression and to develop more effective therapeutic interventions.
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Tumor-Immune
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Heterogeneity / Evolution
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Drug Resistance / Sensitivity
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Metastasis
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Micro Environment
News
- 12.06.18 | Summer Fellowship Opportunity with Cancer Systems Biology Consortium and Physical Sciences in Oncology Network
- 11.19.18 | NIH-funded Short Courses at UCI
- 10.22.18 | Free Workshop on Dissecting Tumor Heterogeneity
- 10.22.18 | Stanford PRISM program: Postdoctoral Recruitment Initiative in Science and Medicine
Publications
- Modulators of Redox Metabolism in Head and Neck Cancer. Chen X, Mims J, Huang X, Singh N, Motea E, Planchon SM, Beg M, Tsang AW, Porosnicu M, Kemp ML, Boothman DA, Furdui CM. Antioxid Redox Signal. 2018 Dec 1;29(16):1660-1690.
- Mechanisms for the epigenetic inheritance of stress response in single cells. Xue Y, Acar M. Curr Genet. 2018 Dec;64(6):1221-1228.