Dr. Andrea Califano Investigates Regulatory Mechanisms in Cancer Using Computational Algorithms and Biological Experiments

Columbia University CSBC Investigator Andrea Califano, Ph.D., studies proteins that control cellular networks, known as master regulators, and their role in cancer progression.

As a post-doc in physics at MIT, he was excited by the emerging areas of artificial intelligence and machine vision. Then, he worked for IBM, first developing algorithms for pattern discovery and then applying mathematical models to biological data. However, according to him, he transitioned to academic systems biology research because, “I wanted to put my money where my mouth was and have a chance to experimentally validate my computational predictions.”