Dr. Peter Sorger Constructs Models of Responsiveness and Resistance to Cancer Therapies

Peter Sorger, Ph.D., a CSBC investigator at Harvard Medical School, constructs and validates network-level models of pharmacological actions. As a graduate student in England, he characterized one of the first eukaryotic transcription factors involved in stress responses. Later, he used his critical thinking and analytical skills to investigate chromosome segregation as a postdoc in the lab of Dr. Harold Varmus. This eventually led him to studies of cell transformation, cell death, and signal transduction. Now, he uses systems approaches to understand the mechanisms of response and resistance to cancer treatments. In this interview he discusses his views on cancer systems biology, shares his perspective on collaboration, and describes his CSBC research.