U54 Research Centers – CSBC

Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types.

Scarless genome editing: progress towards understanding genotype-phenotype relationships.

Mechanisms for the epigenetic inheritance of stress response in single cells.

The number of titrated microRNA species dictates ceRNA regulation

Programmable sequential mutagenesis by inducible Cpf1 crRNA array inversion.

GFPT2-expressing cancer-associated fibroblasts mediate metabolic reprogramming in human lung adenocarcinoma.

Comparing side chain packing in soluble proteins, protein-protein interfaces, and transmembrane proteins

Cross-Cohort Analysis Identifies a TEAD4-MYCN Positive Feedback Loop as the Core Regulatory Element of High-Risk Neuroblastoma

DRUG-NEM: Optimizing drug combinations using single-cell perturbation response to account for intratumoral heterogeneity

Systematic Evaluation of Molecular Networks for Discovery of Disease Genes