CSBC Supported Publications

Publications

  • 2021 | Irreversibility in dynamical phases and transitions. Seara, DS, Machta, BB, Murrell, MP Nat Commun 12 (1): 392. doi: 10.1038/s41467-020-20281-2. PubMed PMID:33452238
  • 2020 | Genomic Alterations during the In Situ to Invasive Ductal Breast Carcinoma Transition Shaped by the Immune System. Trinh, A, Gil Del Alcazar, CR, Shukla, SA, Chin, K, Chang, YH, Thibault, G, Eng, J, Jovanović, B, Aldaz, CM, Park, SY, Jeong, J, Wu, C, Gray, J, Polyak, K Mol Cancer Res : . doi: 10.1158/1541-7786.MCR-20-0949. PubMed PMID:33443130
  • 2020 | Co-stimulatory and co-inhibitory immune markers in solid tumors with MET alterations. Reckamp, KL, McQuerry, JA, Mambetsariev, I, Pharaon, R, Yost, SE, Fricke, J, Mirzapoiazova, T, Pillai, RK, Khan, Z, Fakih, M, Yuan, Y, Koczywas, M, Massarelli, E, Kulkarni, P, Pal, SK, Sattler, M, Bild, A, Salgia, R Future Sci OA 7 (2): FSO662. doi: 10.2144/fsoa-2020-0159. PubMed PMID:33437521 PubMed Central PMC7787173
  • 2021 | Mass spectrometry-based protein-protein interaction networks for the study of human diseases. Richards, AL, Eckhardt, M, Krogan, NJ Mol Syst Biol 17 (1): e8792. doi: 10.15252/msb.20188792. PubMed PMID:33434350
  • 2021 | HiDeF: identifying persistent structures in multiscale 'omics data. Zheng, F, Zhang, S, Churas, C, Pratt, D, Bahar, I, Ideker, T Genome Biol 22 (1): 21. doi: 10.1186/s13059-020-02228-4. PubMed PMID:33413539 PubMed Central PMC7789082
  • 2021 | Genetic screening for single-cell variability modulators driving therapy resistance. Torre, EA, Arai, E, Bayatpour, S, Jiang, CL, Beck, LE, Emert, BL, Shaffer, SM, Mellis, IA, Fane, ME, Alicea, GM, Budinich, KA, Weeraratna, AT, Shi, J, Raj, A Nat Genet 53 (1): 76-85. doi: 10.1038/s41588-020-00749-z. PubMed PMID:33398196 PubMed Central PMC7796998
  • 2021 | The aging transcriptome and cellular landscape of the human lung in relation to SARS-CoV-2. Chow, RD, Majety, M, Chen, S Nat Commun 12 (1): 4. doi: 10.1038/s41467-020-20323-9. PubMed PMID:33397975 PubMed Central PMC7782551
  • 2020 | Two Stream Active Query Suggestion for Active Learning in Connectomics. Lin, Z, Wei, D, Jang, WD, Zhou, S, Chen, X, Wang, X, Schalek, R, Berger, D, Matejek, B, Kamentsky, L, Peleg, A, Haehn, D, Jones, T, Parag, T, Lichtman, J, Pfister, H Comput Vis ECCV 12363 : 103-120. doi: 10.1007/978-3-030-58523-5_7. PubMed PMID:33345257 PubMed Central PMC7746018
  • 2020 | Addressing BBB Heterogeneity: A New Paradigm for Drug Delivery to Brain Tumors. Griffith, JI, Rathi, S, Zhang, W, Zhang, W, Drewes, LR, Sarkaria, JN, Elmquist, WF Pharmaceutics 12 (12): . doi: 10.3390/pharmaceutics12121205. PubMed PMID:33322488 PubMed Central PMC7763839
  • 2021 | Transcriptional response modules characterize IL-1β and IL-6 activity in COVID-19. Bell, LCK, Meydan, C, Kim, J, Foox, J, Butler, D, Mason, CE, Shapira, SD, Noursadeghi, M, Pollara, G iScience 24 (1): 101896. doi: 10.1016/j.isci.2020.101896. PubMed PMID:33319166 PubMed Central PMC7721347
  • 2020 | A Call to Action: Dismantling Racial Injustices in Preclinical Research and Clinical Care of Black Patients Living with Small Cell Lung Cancer. Thomas, PL, Madubata, CJ, Aldrich, MC, Lee, MM, Owonikoko, TK, Minna, JD, Rudin, CM, Sage, J, Lovly, CM Cancer Discov : . doi: 10.1158/2159-8290.CD-20-1592. PubMed PMID:33318034
  • 2020 | Automated Measurements of Key Morphological Features of Human Embryos for IVF. Leahy, BD, Jang, WD, Yang, HY, Struyven, R, Wei, D, Sun, Z, Lee, KR, Royston, C, Cam, L, Kalma, Y, Azem, F, Ben-Yosef, D, Pfister, H, Needleman, D Med Image Comput Comput Assist Interv 12265 : 25-35. doi: 10.1007/978-3-030-59722-1_3. PubMed PMID:33313603 PubMed Central PMC7732604
  • 2020 | Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity. Ringel, AE, Drijvers, JM, Baker, GJ, Catozzi, A, García-Cañaveras, JC, Gassaway, BM, Miller, BC, Juneja, VR, Nguyen, TH, Joshi, S, Yao, CH, Yoon, H, Sage, PT, LaFleur, MW, Trombley, JD, Jacobson, CA, Maliga, Z, Gygi, SP, Sorger, PK, Rabinowitz, JD, Sharpe, AH, Haigis, MC Cell 183 (7): 1848-1866.e26. doi: 10.1016/j.cell.2020.11.009. PubMed PMID:33301708
  • 2020 | Methodological Advancements for Investigating Intra-tumoral Heterogeneity in Breast Cancer at the Bench and Bedside. Baek, M, Chang, JT, Echeverria, GV J Mammary Gland Biol Neoplasia : . doi: 10.1007/s10911-020-09470-3. PubMed PMID:33300087
  • 2020 | Transcriptional response modules characterise IL-1β and IL-6 activity in COVID-19. Bell, LC, Meydan, C, Kim, J, Foox, J, Butler, D, Mason, CE, Shapira, SD, Noursadeghi, M, Pollara, G bioRxiv : . doi: 10.1101/2020.07.22.202275. PubMed PMID:33299992 PubMed Central PMC7724660
  • 2020 | Gene regulation gravitates toward either addition or multiplication when combining the effects of two signals. Sanford, EM, Emert, BL, Coté, A, Raj, A Elife 9 : . doi: 10.7554/eLife.59388. PubMed PMID:33284110 PubMed Central PMC7771960
  • 2020 | Can some microbes promote host stress and benefit evolutionarily from this strategy?. Aktipis, A, Guevara Beltran, D Bioessays : e2000188. doi: 10.1002/bies.202000188. PubMed PMID:33283894
  • 2020 | MitoEM Dataset: Large-scale 3D Mitochondria Instance Segmentation from EM Images. Wei, D, Lin, Z, Franco-Barranco, D, Wendt, N, Liu, X, Yin, W, Huang, X, Gupta, A, Jang, WD, Wang, X, Arganda-Carreras, I, Lichtman, JW, Pfister, H Med Image Comput Comput Assist Interv 12265 : 66-76. doi: 10.1007/978-3-030-59722-1_7. PubMed PMID:33283212 PubMed Central PMC7713709
  • 2020 | Channel Embedding for Informative Protein Identification from Highly Multiplexed Images. Magid, SA, Jang, WD, Schapiro, D, Wei, D, Tompkin, J, Sorger, PK, Pfister, H Med Image Comput Comput Assist Interv 12265 : 3-13. doi: 10.1007/978-3-030-59722-1_1. PubMed PMID:33283211 PubMed Central PMC7713713
  • 2020 | Pharmacologic Screening Identifies Metabolic Vulnerabilities of CD8+ T Cells. Drijvers, JM, Gillis, JE, Muijlwijk, T, Nguyen, TH, Gaudiano, EF, Harris, IS, LaFleur, MW, Ringel, AE, Yao, CH, Kurmi, K, Juneja, VR, Trombley, JD, Haigis, MC, Sharpe, AH Cancer Immunol Res : . doi: 10.1158/2326-6066.CIR-20-0384. PubMed PMID:33277233
  • 2020 | VISTA: VIsual Semantic Tissue Analysis for pancreatic disease quantification in murine cohorts. Ternes, L, Huang, G, Lanciault, C, Thibault, G, Riggers, R, Gray, JW, Muschler, J, Chang, YH Sci Rep 10 (1): 20904. doi: 10.1038/s41598-020-78061-3. PubMed PMID:33262400 PubMed Central PMC7708430
  • 2020 | Myeloid-derived suppressor cells are a major source of Wnt5A in the melanoma microenvironment and depend on Wnt5A for full suppressive activity. Douglass, SM, Fane, ME, Sanseviero, E, Ecker, BL, Kugel, CH, Behera, R, Kumar, V, Tcyganov, EN, Yin, X, Liu, Q, Chhabra, Y, Alicea, GM, Kuruvilla, R, Gabrilovich, DI, Weeraratna, AT Cancer Res : . doi: 10.1158/0008-5472.CAN-20-1238. PubMed PMID:33262126
  • 2020 | Head and neck squamous cell carcinoma. Johnson, DE, Burtness, B, Leemans, CR, Lui, VWY, Bauman, JE, Grandis, JR Nat Rev Dis Primers 6 (1): 92. doi: 10.1038/s41572-020-00224-3. PubMed PMID:33243986
  • 2020 | The gut microbiota is associated with immune cell dynamics in humans. Schluter, J, Peled, JU, Taylor, BP, Markey, KA, Smith, M, Taur, Y, Niehus, R, Staffas, A, Dai, A, Fontana, E, Amoretti, LA, Wright, RJ, Morjaria, S, Fenelus, M, Pessin, MS, Chao, NJ, Lew, M, Bohannon, L, Bush, A, Sung, AD, Hohl, TM, Perales, MA, van den Brink, MRM, Xavier, JB Nature 588 (7837): 303-307. doi: 10.1038/s41586-020-2971-8. PubMed PMID:33239790 PubMed Central PMC7725892
  • 2021 | Concurrent Dexamethasone Limits the Clinical Benefit of Immune Checkpoint Blockade in Glioblastoma. Iorgulescu, JB, Gokhale, PC, Speranza, MC, Eschle, BK, Poitras, MJ, Wilkens, MK, Soroko, KM, Chhoeu, C, Knott, A, Gao, Y, Lim-Fat, MJ, Baker, GJ, Bonal, DM, Nguyen, QD, Grant, GRL, Ligon, KL, Sorger, PK, Chiocca, EA, Anderson, AC, Kirschmeier, PT, Sharpe, AH, Freeman, GJ, Reardon, DA Clin Cancer Res 27 (1): 276-287. doi: 10.1158/1078-0432.CCR-20-2291. PubMed PMID:33239433
  • 2020 | Comparing the Efficacy of Cancer Therapies between Subgroups in Basket Trials. Palmer, AC, Plana, D, Sorger, PK Cell Syst 11 (5): 449-460.e2. doi: 10.1016/j.cels.2020.09.003. PubMed PMID:33220857
  • 2020 | Transmissible cancers and the evolution of sex under the Red Queen hypothesis. Aubier, TG, Galipaud, M, Erten, EY, Kokko, H PLoS Biol 18 (11): e3000916. doi: 10.1371/journal.pbio.3000916. PubMed PMID:33211684 PubMed Central PMC7676742
  • 2020 | Lifetime cancer prevalence and life history traits in mammals. Boddy, AM, Abegglen, LM, Pessier, AP, Aktipis, A, Schiffman, JD, Maley, CC, Witte, C Evol Med Public Health 2020 (1): 187-195. doi: 10.1093/emph/eoaa015. PubMed PMID:33209304 PubMed Central PMC7652303
  • 2020 | A Random Matrix Theory Approach to Denoise Single-Cell Data. Aparicio, L, Bordyuh, M, Blumberg, AJ, Rabadan, R Patterns (N Y) 1 (3): 100035. doi: 10.1016/j.patter.2020.100035. PubMed PMID:33205104 PubMed Central PMC7660363
  • 2020 | The MOBSTER R package for tumour subclonal deconvolution from bulk DNA whole-genome sequencing data. Caravagna, G, Sanguinetti, G, Graham, TA, Sottoriva, A BMC Bioinformatics 21 (1): 531. doi: 10.1186/s12859-020-03863-1. PubMed PMID:33203356 PubMed Central PMC7672894
  • 2020 | High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue. Liu, Y, Yang, M, Deng, Y, Su, G, Enninful, A, Guo, CC, Tebaldi, T, Zhang, D, Kim, D, Bai, Z, Norris, E, Pan, A, Li, J, Xiao, Y, Halene, S, Fan, R Cell 183 (6): 1665-1681.e18. doi: 10.1016/j.cell.2020.10.026. PubMed PMID:33188776 PubMed Central PMC7736559
  • 2020 | Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA. Yuan, S, Peng, L, Park, JJ, Hu, Y, Devarkar, SC, Dong, MB, Shen, Q, Wu, S, Chen, S, Lomakin, IB, Xiong, Y Mol Cell 80 (6): 1055-1066.e6. doi: 10.1016/j.molcel.2020.10.034. PubMed PMID:33188728
  • 2020 | Hyperprogression on immunotherapy with complete response to chemotherapy in a NSCLC patient with high PD-L1 and STK11: A case report. Fricke, J, Mambetsariev, I, Pharaon, R, Subbiah, S, Rajurkar, S, Salgia, R Medicine (Baltimore) 99 (46): e22323. doi: 10.1097/MD.0000000000022323. PubMed PMID:33181636 PubMed Central PMC7668523
  • 2020 | Turnover modulates the need for a cost of resistance in adaptive therapy. Strobl, MAR, West, J, Viossat, Y, Damaghi, M, Robertson-Tessi, M, Brown, JS, Gatenby, RA, Maini, PK, Anderson, ARA Cancer Res : . doi: 10.1158/0008-5472.CAN-20-0806. PubMed PMID:33172930
  • 2020 | The effects of age and systemic metabolism on anti-tumor T cell responses. Drijvers, JM, Sharpe, AH, Haigis, MC Elife 9 : . doi: 10.7554/eLife.62420. PubMed PMID:33170123 PubMed Central PMC7655106
  • 2020 | Chromatin regulatory genes differentially interact in networks to facilitate distinct GAL1 activity and noise profiles. Moreno, DF, Acar, M Curr Genet : . doi: 10.1007/s00294-020-01124-5. PubMed PMID:33159551
  • 2020 | Systematic elucidation of neuron-astrocyte interaction in models of amyotrophic lateral sclerosis using multi-modal integrated bioinformatics workflow. Mishra, V, Re, DB, Le Verche, V, Alvarez, MJ, Vasciaveo, A, Jacquier, A, Doulias, PT, Greco, TM, Nizzardo, M, Papadimitriou, D, Nagata, T, Rinchetti, P, Perez-Torres, EJ, Politi, KA, Ikiz, B, Clare, K, Than, ME, Corti, S, Ischiropoulos, H, Lotti, F, Califano, A, Przedborski, S Nat Commun 11 (1): 5579. doi: 10.1038/s41467-020-19177-y. PubMed PMID:33149111 PubMed Central PMC7642391
  • 2020 | Rapid progression of disease from immunotherapy following targeted therapy: insights into treatment management and sequence. Pharaon, R, Mambetsariev, I, Fricke, J, Salgia, R J Thorac Dis 12 (9): 5096-5103. doi: 10.21037/jtd.2019.08.14. PubMed PMID:33145086 PubMed Central PMC7578509
  • 2020 | Role of immunotherapy and co-mutations on KRAS-mutant non-small cell lung cancer survival. Amanam, I, Mambetsariev, I, Gupta, R, Achuthan, S, Wang, Y, Pharaon, R, Massarelli, E, Koczywas, M, Reckamp, K, Salgia, R J Thorac Dis 12 (9): 5086-5095. doi: 10.21037/jtd.2020.04.18. PubMed PMID:33145085 PubMed Central PMC7578487
  • 2020 | Identifying the spatial and temporal dynamics of molecularly-distinct glioblastoma sub-populations. Morris, B, Curtin, L, Hawkins-Daarud, A, Hubbard, ME, Rahman, R, Smith, SJ, Auer, D, Tran, NL, Hu, LS, Eschbacher, JM, Smith, KA, Stokes, A, Swanson, KR, Owen, MR Math Biosci Eng 17 (5): 4905-4941. doi: 10.3934/mbe.2020267. PubMed PMID:33120534
  • 2020 | ACE2 localizes to the respiratory cilia and is not increased by ACE inhibitors or ARBs. Lee, IT, Nakayama, T, Wu, CT, Goltsev, Y, Jiang, S, Gall, PA, Liao, CK, Shih, LC, Schürch, CM, McIlwain, DR, Chu, P, Borchard, NA, Zarabanda, D, Dholakia, SS, Yang, A, Kim, D, Chen, H, Kanie, T, Lin, CD, Tsai, MH, Phillips, KM, Kim, R, Overdevest, JB, Tyler, MA, Yan, CH, Lin, CF, Lin, YT, Bau, DT, Tsay, GJ, Patel, ZM, Tsou, YA, Tzankov, A, Matter, MS, Tai, CJ, Yeh, TH, Hwang, PH, Nolan, GP, Nayak, JV, Jackson, PK Nat Commun 11 (1): 5453. doi: 10.1038/s41467-020-19145-6. PubMed PMID:33116139 PubMed Central PMC7595232
  • 2020 | Epigenetic Mechanisms Contribute to Evolutionary Adaptation of Gene Network Activity under Environmental Selection. Luo, X, Song, R, Moreno, DF, Ryu, HY, Hochstrasser, M, Acar, M Cell Rep 33 (4): 108306. doi: 10.1016/j.celrep.2020.108306. PubMed PMID:33113358 PubMed Central PMC7656290
  • 2020 | Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma Cells. Gerosa, L, Chidley, C, Fröhlich, F, Sanchez, G, Lim, SK, Muhlich, J, Chen, JY, Vallabhaneni, S, Baker, GJ, Schapiro, D, Atanasova, MI, Chylek, LA, Shi, T, Yi, L, Nicora, CD, Claas, A, Ng, TSC, Kohler, RH, Lauffenburger, DA, Weissleder, R, Miller, MA, Qian, WJ, Wiley, HS, Sorger, PK Cell Syst 11 (5): 478-494.e9. doi: 10.1016/j.cels.2020.10.002. PubMed PMID:33113355
  • 2020 | sFRP2 Supersedes VEGF as an Age-related Driver of Angiogenesis in Melanoma, Affecting Response to Anti-VEGF Therapy in Older Patients. Fane, ME, Ecker, BL, Kaur, A, Marino, GE, Alicea, GM, Douglass, SM, Chhabra, Y, Webster, MR, Marshall, A, Colling, R, Espinosa, O, Coupe, N, Maroo, N, Campo, L, Middleton, MR, Corrie, P, Xu, X, Karakousis, GC, Weeraratna, AT Clin Cancer Res 26 (21): 5709-5719. doi: 10.1158/1078-0432.CCR-20-0446. PubMed PMID:33097493 PubMed Central PMC7642114
  • 2020 | Predicting Drug Response and Synergy Using a Deep Learning Model of Human Cancer Cells. Kuenzi, BM, Park, J, Fong, SH, Sanchez, KS, Lee, J, Kreisberg, JF, Ma, J, Ideker, T Cancer Cell 38 (5): 672-684.e6. doi: 10.1016/j.ccell.2020.09.014. PubMed PMID:33096023 PubMed Central PMC7737474
  • 2020 | Pharmacologic profiling of patient-derived xenograft models of primary treatment-naïve triple-negative breast cancer. Powell, RT, Redwood, A, Liu, X, Guo, L, Cai, S, Zhou, X, Tu, Y, Zhang, X, Qi, Y, Jiang, Y, Echeverria, G, Feng, N, Ma, X, Giuliani, V, Marszalek, JR, Heffernan, TP, Vellano, CP, White, JB, Stephan, C, Davies, PJ, Moulder, S, Symmans, WF, Chang, JT, Piwnica-Worms, H Sci Rep 10 (1): 17899. doi: 10.1038/s41598-020-74882-4. PubMed PMID:33087803 PubMed Central PMC7578025
  • 2020 | Divergent Resistance Mechanisms to Immunotherapy Explain Responses in Different Skin Cancers. Dollinger, E, Bergman, D, Zhou, P, Atwood, SX, Nie, Q Cancers (Basel) 12 (10): . doi: 10.3390/cancers12102946. PubMed PMID:33065980 PubMed Central PMC7599806
  • 2020 | Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques. Aid, M, Busman-Sahay, K, Vidal, SJ, Maliga, Z, Bondoc, S, Starke, C, Terry, M, Jacobson, CA, Wrijil, L, Ducat, S, Brook, OR, Miller, AD, Porto, M, Pellegrini, KL, Pino, M, Hoang, TN, Chandrashekar, A, Patel, S, Stephenson, K, Bosinger, SE, Andersen, H, Lewis, MG, Hecht, JL, Sorger, PK, Martinot, AJ, Estes, JD, Barouch, DH Cell 183 (5): 1354-1366.e13. doi: 10.1016/j.cell.2020.10.005. PubMed PMID:33065030 PubMed Central PMC7546181
  • 2020 | SHIFT: speedy histological-to-immunofluorescent translation of a tumor signature enabled by deep learning. Burlingame, EA, McDonnell, M, Schau, GF, Thibault, G, Lanciault, C, Morgan, T, Johnson, BE, Corless, C, Gray, JW, Chang, YH Sci Rep 10 (1): 17507. doi: 10.1038/s41598-020-74500-3. PubMed PMID:33060677 PubMed Central PMC7566625
  • 2020 | An Integrative Gene Expression and Mathematical Flux Balance Analysis Identifies Targetable Redox Vulnerabilities in Melanoma Cells. Paudel, BB, Lewis, JE, Hardeman, KN, Hayford, CE, Robbins, CJ, Stauffer, PE, Codreanu, SG, Sherrod, SD, McLean, JA, Kemp, ML, Quaranta, V Cancer Res 80 (20): 4565-4577. doi: 10.1158/0008-5472.CAN-19-3588. PubMed PMID:33060170
  • 2020 | A Sweep of Earth's Virome Reveals Host-Guided Viral Protein Structural Mimicry and Points to Determinants of Human Disease. Lasso, G, Honig, B, Shapira, SD Cell Syst : . doi: 10.1016/j.cels.2020.09.006. PubMed PMID:33053371 PubMed Central PMC7552982
  • 2020 | Dynamics of nevus development implicate cell cooperation in the growth arrest of transformed melanocytes. Ruiz-Vega, R, Chen, CF, Razzak, E, Vasudeva, P, Krasieva, TB, Shiu, J, Caldwell, MG, Yan, H, Lowengrub, J, Ganesan, AK, Lander, AD Elife 9 : . doi: 10.7554/eLife.61026. PubMed PMID:33047672 PubMed Central PMC7553774
  • 2020 | Landscape of coordinated immune responses to H1N1 challenge in humans. Rahil, Z, Leylek, R, Schürch, CM, Chen, H, Bjornson-Hooper, Z, Christensen, SR, Gherardini, PF, Bhate, SS, Spitzer, MH, Fragiadakis, GK, Mukherjee, N, Kim, N, Jiang, S, Yo, J, Gaudilliere, B, Affrime, M, Bock, B, Hensley, SE, Idoyaga, J, Aghaeepour, N, Kim, K, Nolan, GP, McIlwain, DR J Clin Invest 130 (11): 5800-5816. doi: 10.1172/JCI137265. PubMed PMID:33044226 PubMed Central PMC7598057
  • 2020 | Monitoring and modeling of lymphocytic leukemia cell bioenergetics reveals decreased ATP synthesis during cell division. Kang, JH, Katsikis, G, Li, Z, Sapp, KM, Stockslager, MA, Lim, D, Vander Heiden, MG, Yaffe, MB, Manalis, SR, Miettinen, TP Nat Commun 11 (1): 4983. doi: 10.1038/s41467-020-18769-y. PubMed PMID:33020492 PubMed Central PMC7536222
  • 2020 | Considerations for the Selection and Use of Disinfectants Against SARS-CoV-2 in a Health Care Setting. Tyan, K, Levin, A, Avalos-Pacheco, A, Plana, D, Rand, EA, Yang, H, Maliszewski, LE, Chylek, LA, Atta, L, Tye, MA, Carmack, MM, Oglesby, NS, Burgin, S, Yu, SH, LeBoeuf, NR, Kemp, JM Open Forum Infect Dis 7 (9): ofaa396. doi: 10.1093/ofid/ofaa396. PubMed PMID:32989420 PubMed Central PMC7499694
  • 2020 | A web tool for the design of prime-editing guide RNAs. Chow, RD, Chen, JS, Shen, J, Chen, S Nat Biomed Eng : . doi: 10.1038/s41551-020-00622-8. PubMed PMID:32989284
  • 2020 | Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism. Chou, CW, Tan, X, Hung, CN, Lieberman, B, Chen, M, Kusi, M, Mitsuya, K, Lin, CL, Morita, M, Liu, Z, Chen, CL, Huang, TH Cancers (Basel) 12 (9): . doi: 10.3390/cancers12092715. PubMed PMID:32971831 PubMed Central PMC7564175
  • 2020 | The 3D genomic landscape of differential response to EGFR/HER2 inhibition in endocrine-resistant breast cancer cells. Yang, Y, Choppavarapu, L, Fang, K, Naeini, AS, Nosirov, B, Li, J, Yang, K, He, Z, Zhou, Y, Schiff, R, Li, R, Hu, Y, Wang, J, Jin, VX Biochim Biophys Acta Gene Regul Mech 1863 (11): 194631. doi: 10.1016/j.bbagrm.2020.194631. PubMed PMID:32956836 PubMed Central PMC7686120
  • 2020 | Leveraging correlations between variants in polygenic risk scores to detect heterogeneity in GWAS cohorts. Yuan, J, Xing, H, Lamy, AL, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Lencz, T, Pe'er, I PLoS Genet 16 (9): e1009015. doi: 10.1371/journal.pgen.1009015. PubMed PMID:32956347 PubMed Central PMC7529195
  • 2020 | A Non-genetic Mechanism Involving the Integrin β4/Paxillin Axis Contributes to Chemoresistance in Lung Cancer. Mohanty, A, Nam, A, Pozhitkov, A, Yang, L, Srivastava, S, Nathan, A, Wu, X, Mambetsariev, I, Nelson, M, Subbalakshmi, AR, Guo, L, Nasser, MW, Batra, SK, Orban, J, Jolly, MK, Massarelli, E, Kulkarni, P, Salgia, R iScience 23 (9): 101496. doi: 10.1016/j.isci.2020.101496. PubMed PMID:32947124 PubMed Central PMC7502350
  • 2020 | The transcriptomic response of cells to a drug combination is more than the sum of the responses to the monotherapies. Diaz, JE, Ahsen, ME, Schaffter, T, Chen, X, Realubit, RB, Karan, C, Califano, A, Losic, B, Stolovitzky, G Elife 9 : . doi: 10.7554/eLife.52707. PubMed PMID:32945258 PubMed Central PMC7546737
  • 2020 | A Phosphoramidate Strategy Enables Membrane Permeability of a Non-nucleotide Inhibitor of the Prolyl Isomerase Pin1. Schwarz, DMC, Williams, SK, Dillenburg, M, Wagner, CR, Gestwicki, JE ACS Med Chem Lett 11 (9): 1704-1710. doi: 10.1021/acsmedchemlett.0c00170. PubMed PMID:32944137 PubMed Central PMC7488286
  • 2020 | Integrating Mathematical Modeling with High-Throughput Imaging Explains How Polyploid Populations Behave in Nutrient-Sparse Environments. Kimmel, GJ, Dane, M, Heiser, LM, Altrock, PM, Andor, N Cancer Res 80 (22): 5109-5120. doi: 10.1158/0008-5472.CAN-20-1231. PubMed PMID:32938640 PubMed Central PMC7671819
  • 2020 | Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 disease severity. Inde, Z, Yapp, C, Joshi, GN, Spetz, J, Fraser, C, Deskin, B, Ghelfi, E, Sodhi, C, Hackam, D, Kobzik, L, Croker, B, Brownfield, D, Jia, H, Sarosiek, KA bioRxiv : . doi: 10.1101/2020.09.13.276923. PubMed PMID:32935109 PubMed Central PMC7491524
  • 2020 | Evolutionary dynamics of neoantigens in growing tumors. Lakatos, E, Williams, MJ, Schenck, RO, Cross, WCH, Househam, J, Zapata, L, Werner, B, Gatenbee, C, Robertson-Tessi, M, Barnes, CP, Anderson, ARA, Sottoriva, A, Graham, TA Nat Genet 52 (10): 1057-1066. doi: 10.1038/s41588-020-0687-1. PubMed PMID:32929288
  • 2020 | Oncoprotein-specific molecular interaction maps (SigMaps) for cancer network analyses. Broyde, J, Simpson, DR, Murray, D, Paull, EO, Chu, BW, Tagore, S, Jones, SJ, Griffin, AT, Giorgi, FM, Lachmann, A, Jackson, P, Sweet-Cordero, EA, Honig, B, Califano, A Nat Biotechnol : . doi: 10.1038/s41587-020-0652-7. PubMed PMID:32929263
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