CSBC Supported Publications

Publications

  • 2021 | Compilation of longitudinal microbiota data and hospitalome from hematopoietic cell transplantation patients. Liao, C, Taylor, BP, Ceccarani, C, Fontana, E, Amoretti, LA, Wright, RJ, Gomes, ALC, Peled, JU, Perales, MA, van den Brink, MRM, Littmann, E, Pamer, EG, Schluter, J, Xavier, JB Sci Data 8 (1): 71. doi: 10.1038/s41597-021-00860-8. PubMed PMID:33654104
  • 2021 | Multimodal pooled Perturb-CITE-seq screens in patient models define mechanisms of cancer immune evasion. Frangieh, CJ, Melms, JC, Thakore, PI, Geiger-Schuller, KR, Ho, P, Luoma, AM, Cleary, B, Jerby-Arnon, L, Malu, S, Cuoco, MS, Zhao, M, Ager, CR, Rogava, M, Hovey, L, Rotem, A, Bernatchez, C, Wucherpfennig, KW, Johnson, BE, Rozenblatt-Rosen, O, Schadendorf, D, Regev, A, Izar, B Nat Genet : . doi: 10.1038/s41588-021-00779-1. PubMed PMID:33649592
  • 2021 | Variability within rare cell states enables multiple paths toward drug resistance. Emert, BL, Cote, CJ, Torre, EA, Dardani, IP, Jiang, CL, Jain, N, Shaffer, SM, Raj, A Nat Biotechnol : . doi: 10.1038/s41587-021-00837-3. PubMed PMID:33619394
  • 2021 | Stability Analysis of a Signaling Circuit with Dual Species of GTPase Switches. Stolerman, LM, Ghosh, P, Rangamani, P Bull Math Biol 83 (4): 34. doi: 10.1007/s11538-021-00864-w. PubMed PMID:33609194
  • 2021 | Regulation of PTEN translation by PI3K signaling maintains pathway homeostasis. Mukherjee, R, Vanaja, KG, Boyer, JA, Gadal, S, Solomon, H, Chandarlapaty, S, Levchenko, A, Rosen, N Mol Cell 81 (4): 708-723.e5. doi: 10.1016/j.molcel.2021.01.033. PubMed PMID:33606974
  • 2021 | Uncertainty quantification in the radiogenomics modeling of EGFR amplification in glioblastoma. Hu, LS, Wang, L, Hawkins-Daarud, A, Eschbacher, JM, Singleton, KW, Jackson, PR, Clark-Swanson, K, Sereduk, CP, Peng, S, Wang, P, Wang, J, Baxter, LC, Smith, KA, Mazza, GL, Stokes, AM, Bendok, BR, Zimmerman, RS, Krishna, C, Porter, AB, Mrugala, MM, Hoxworth, JM, Wu, T, Tran, NL, Swanson, KR, Li, J Sci Rep 11 (1): 3932. doi: 10.1038/s41598-021-83141-z. PubMed PMID:33594116 PubMed Central PMC7886858
  • 2021 | Machine learning identifies candidates for drug repurposing in Alzheimer's disease. Rodriguez, S, Hug, C, Todorov, P, Moret, N, Boswell, SA, Evans, K, Zhou, G, Johnson, NT, Hyman, BT, Sorger, PK, Albers, MW, Sokolov, A Nat Commun 12 (1): 1033. doi: 10.1038/s41467-021-21330-0. PubMed PMID:33589615 PubMed Central PMC7884393
  • 2021 | Evolved Resistance to Placental Invasion Secondarily Confers Increased Survival in Melanoma Patients. Suhail, Y, Afzal, J, Kshitiz, J Clin Med 10 (4): . doi: 10.3390/jcm10040595. PubMed PMID:33562461 PubMed Central PMC7915120
  • 2021 | shinyDepMap, a tool to identify targetable cancer genes and their functional connections from Cancer Dependency Map data. Shimada, K, Bachman, JA, Muhlich, JL, Mitchison, TJ Elife 10 : . doi: 10.7554/eLife.57116. PubMed PMID:33554860 PubMed Central PMC7924953
  • 2021 | A gene-environment-induced epigenetic program initiates tumorigenesis. Alonso-Curbelo, D, Ho, YJ, Burdziak, C, Maag, JLV, Morris, JP 4th, Chandwani, R, Chen, HA, Tsanov, KM, Barriga, FM, Luan, W, Tasdemir, N, Livshits, G, Azizi, E, Chun, J, Wilkinson, JE, Mazutis, L, Leach, SD, Koche, R, Pe'er, D, Lowe, SW Nature 590 (7847): 642-648. doi: 10.1038/s41586-020-03147-x. PubMed PMID:33536616
  • 2021 | The improbable targeted therapy: KRAS as an emerging target in non-small cell lung cancer (NSCLC). Salgia, R, Pharaon, R, Mambetsariev, I, Nam, A, Sattler, M Cell Rep Med 2 (1): 100186. doi: 10.1016/j.xcrm.2020.100186. PubMed PMID:33521700 PubMed Central PMC7817862
  • 2021 | Optimal experimental design for mathematical models of haematopoiesis. Lomeli, LM, Iniguez, A, Tata, P, Jena, N, Liu, ZY, Van Etten, R, Lander, AD, Shahbaba, B, Lowengrub, JS, Minin, VN J R Soc Interface 18 (174): 20200729. doi: 10.1098/rsif.2020.0729. PubMed PMID:33499768 PubMed Central PMC7879761
  • 2021 | PEtab-Interoperable specification of parameter estimation problems in systems biology. Schmiester, L, Schälte, Y, Bergmann, FT, Camba, T, Dudkin, E, Egert, J, Fröhlich, F, Fuhrmann, L, Hauber, AL, Kemmer, S, Lakrisenko, P, Loos, C, Merkt, S, Müller, W, Pathirana, D, Raimúndez, E, Refisch, L, Rosenblatt, M, Stapor, PL, Städter, P, Wang, D, Wieland, FG, Banga, JR, Timmer, J, Villaverde, AF, Sahle, S, Kreutz, C, Hasenauer, J, Weindl, D PLoS Comput Biol 17 (1): e1008646. doi: 10.1371/journal.pcbi.1008646. PubMed PMID:33497393 PubMed Central PMC7864467
  • 2021 | Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma. Jerby-Arnon, L, Neftel, C, Shore, ME, Weisman, HR, Mathewson, ND, McBride, MJ, Haas, B, Izar, B, Volorio, A, Boulay, G, Cironi, L, Richman, AR, Broye, LC, Gurski, JM, Luo, CC, Mylvaganam, R, Nguyen, L, Mei, S, Melms, JC, Georgescu, C, Cohen, O, Buendia-Buendia, JE, Segerstolpe, A, Sud, M, Cuoco, MS, Labes, D, Gritsch, S, Zollinger, DR, Ortogero, N, Beechem, JM, Petur Nielsen, G, Chebib, I, Nguyen-Ngoc, T, Montemurro, M, Cote, GM, Choy, E, Letovanec, I, Cherix, S, Wagle, N, Sorger, PK, Haynes, AB, Mullen, JT, Stamenkovic, I, Rivera, MN, Kadoch, C, Wucherpfennig, KW, Rozenblatt-Rosen, O, Suvà, ML, Riggi, N, Regev, A Nat Med 27 (2): 289-300. doi: 10.1038/s41591-020-01212-6. PubMed PMID:33495604
  • 2021 | GECO: gene expression clustering optimization app for non-linear data visualization of patterns. Habowski, AN, Habowski, TJ, Waterman, ML BMC Bioinformatics 22 (1): 29. doi: 10.1186/s12859-020-03951-2. PubMed PMID:33494695 PubMed Central PMC7831185
  • 2021 | Analysis of SteraMist ionized hydrogen peroxide technology in the sterilization of N95 respirators and other PPE. Cramer, AK, Plana, D, Yang, H, Carmack, MM, Tian, E, Sinha, MS, Krikorian, D, Turner, D, Mo, J, Li, J, Gupta, R, Manning, H, Bourgeois, FT, Yu, SH, Sorger, PK, LeBoeuf, NR Sci Rep 11 (1): 2051. doi: 10.1038/s41598-021-81365-7. PubMed PMID:33479334 PubMed Central PMC7819989
  • 2021 | Personalized Genome-Scale Metabolic Models Identify Targets of Redox Metabolism in Radiation-Resistant Tumors. Lewis, JE, Forshaw, TE, Boothman, DA, Furdui, CM, Kemp, ML Cell Syst 12 (1): 68-81.e11. doi: 10.1016/j.cels.2020.12.001. PubMed PMID:33476554 PubMed Central PMC7905848
  • 2021 | The harsh microenvironment in early breast cancer selects for a Warburg phenotype. Damaghi, M, West, J, Robertson-Tessi, M, Xu, L, Ferrall-Fairbanks, MC, Stewart, PA, Persi, E, Fridley, BL, Altrock, PM, Gatenby, RA, Sims, PA, Anderson, ARA, Gillies, RJ Proc Natl Acad Sci U S A 118 (3): . doi: 10.1073/pnas.2011342118. PubMed PMID:33452133 PubMed Central PMC7826394
  • 2020 | Genomic Alterations during the In Situ to Invasive Ductal Breast Carcinoma Transition Shaped by the Immune System. Trinh, A, Gil Del Alcazar, CR, Shukla, SA, Chin, K, Chang, YH, Thibault, G, Eng, J, Jovanović, B, Aldaz, CM, Park, SY, Jeong, J, Wu, C, Gray, J, Polyak, K Mol Cancer Res : . doi: 10.1158/1541-7786.MCR-20-0949. PubMed PMID:33443130
  • 2020 | Co-stimulatory and co-inhibitory immune markers in solid tumors with MET alterations. Reckamp, KL, McQuerry, JA, Mambetsariev, I, Pharaon, R, Yost, SE, Fricke, J, Mirzapoiazova, T, Pillai, RK, Khan, Z, Fakih, M, Yuan, Y, Koczywas, M, Massarelli, E, Kulkarni, P, Pal, SK, Sattler, M, Bild, A, Salgia, R Future Sci OA 7 (2): FSO662. doi: 10.2144/fsoa-2020-0159. PubMed PMID:33437521 PubMed Central PMC7787173
  • 2021 | Mass spectrometry-based protein-protein interaction networks for the study of human diseases. Richards, AL, Eckhardt, M, Krogan, NJ Mol Syst Biol 17 (1): e8792. doi: 10.15252/msb.20188792. PubMed PMID:33434350 PubMed Central PMC7803364
  • 2021 | Mammalian cell proliferation requires noncatalytic functions of O-GlcNAc transferase. Levine, ZG, Potter, SC, Joiner, CM, Fei, GQ, Nabet, B, Sonnett, M, Zachara, NE, Gray, NS, Paulo, JA, Walker, S Proc Natl Acad Sci U S A 118 (4): . doi: 10.1073/pnas.2016778118. PubMed PMID:33419956 PubMed Central PMC7848692
  • 2021 | HiDeF: identifying persistent structures in multiscale 'omics data. Zheng, F, Zhang, S, Churas, C, Pratt, D, Bahar, I, Ideker, T Genome Biol 22 (1): 21. doi: 10.1186/s13059-020-02228-4. PubMed PMID:33413539 PubMed Central PMC7789082
  • 2021 | Genetic screening for single-cell variability modulators driving therapy resistance. Torre, EA, Arai, E, Bayatpour, S, Jiang, CL, Beck, LE, Emert, BL, Shaffer, SM, Mellis, IA, Fane, ME, Alicea, GM, Budinich, KA, Weeraratna, AT, Shi, J, Raj, A Nat Genet 53 (1): 76-85. doi: 10.1038/s41588-020-00749-z. PubMed PMID:33398196 PubMed Central PMC7796998
  • 2021 | The aging transcriptome and cellular landscape of the human lung in relation to SARS-CoV-2. Chow, RD, Majety, M, Chen, S Nat Commun 12 (1): 4. doi: 10.1038/s41467-020-20323-9. PubMed PMID:33397975 PubMed Central PMC7782551
  • 2020 | Two Stream Active Query Suggestion for Active Learning in Connectomics. Lin, Z, Wei, D, Jang, WD, Zhou, S, Chen, X, Wang, X, Schalek, R, Berger, D, Matejek, B, Kamentsky, L, Peleg, A, Haehn, D, Jones, T, Parag, T, Lichtman, J, Pfister, H Comput Vis ECCV 12363 : 103-120. doi: 10.1007/978-3-030-58523-5_7. PubMed PMID:33345257 PubMed Central PMC7746018
  • 2020 | Addressing BBB Heterogeneity: A New Paradigm for Drug Delivery to Brain Tumors. Griffith, JI, Rathi, S, Zhang, W, Zhang, W, Drewes, LR, Sarkaria, JN, Elmquist, WF Pharmaceutics 12 (12): . doi: 10.3390/pharmaceutics12121205. PubMed PMID:33322488 PubMed Central PMC7763839
  • 2021 | Transcriptional response modules characterize IL-1β and IL-6 activity in COVID-19. Bell, LCK, Meydan, C, Kim, J, Foox, J, Butler, D, Mason, CE, Shapira, SD, Noursadeghi, M, Pollara, G iScience 24 (1): 101896. doi: 10.1016/j.isci.2020.101896. PubMed PMID:33319166 PubMed Central PMC7721347
  • 2021 | A Call to Action: Dismantling Racial Injustices in Preclinical Research and Clinical Care of Black Patients Living with Small Cell Lung Cancer. Thomas, PL, Madubata, CJ, Aldrich, MC, Lee, MM, Owonikoko, TK, Minna, JD, Rudin, CM, Sage, J, Lovly, CM Cancer Discov 11 (2): 240-244. doi: 10.1158/2159-8290.CD-20-1592. PubMed PMID:33318034 PubMed Central PMC7858238
  • 2020 | Automated Measurements of Key Morphological Features of Human Embryos for IVF. Leahy, BD, Jang, WD, Yang, HY, Struyven, R, Wei, D, Sun, Z, Lee, KR, Royston, C, Cam, L, Kalma, Y, Azem, F, Ben-Yosef, D, Pfister, H, Needleman, D Med Image Comput Comput Assist Interv 12265 : 25-35. doi: 10.1007/978-3-030-59722-1_3. PubMed PMID:33313603 PubMed Central PMC7732604
  • 2020 | Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity. Ringel, AE, Drijvers, JM, Baker, GJ, Catozzi, A, García-Cañaveras, JC, Gassaway, BM, Miller, BC, Juneja, VR, Nguyen, TH, Joshi, S, Yao, CH, Yoon, H, Sage, PT, LaFleur, MW, Trombley, JD, Jacobson, CA, Maliga, Z, Gygi, SP, Sorger, PK, Rabinowitz, JD, Sharpe, AH, Haigis, MC Cell 183 (7): 1848-1866.e26. doi: 10.1016/j.cell.2020.11.009. PubMed PMID:33301708
  • 2020 | Methodological Advancements for Investigating Intra-tumoral Heterogeneity in Breast Cancer at the Bench and Bedside. Baek, M, Chang, JT, Echeverria, GV J Mammary Gland Biol Neoplasia : . doi: 10.1007/s10911-020-09470-3. PubMed PMID:33300087
  • 2020 | Transcriptional response modules characterise IL-1β and IL-6 activity in COVID-19. Bell, LC, Meydan, C, Kim, J, Foox, J, Butler, D, Mason, CE, Shapira, SD, Noursadeghi, M, Pollara, G bioRxiv : . doi: 10.1101/2020.07.22.202275. PubMed PMID:33299992 PubMed Central PMC7724660
  • 2020 | Gene regulation gravitates toward either addition or multiplication when combining the effects of two signals. Sanford, EM, Emert, BL, Coté, A, Raj, A Elife 9 : . doi: 10.7554/eLife.59388. PubMed PMID:33284110 PubMed Central PMC7771960
  • 2021 | Can some microbes promote host stress and benefit evolutionarily from this strategy?. Aktipis, A, Guevara Beltran, D Bioessays 43 (1): e2000188. doi: 10.1002/bies.202000188. PubMed PMID:33283894
  • 2020 | MitoEM Dataset: Large-scale 3D Mitochondria Instance Segmentation from EM Images. Wei, D, Lin, Z, Franco-Barranco, D, Wendt, N, Liu, X, Yin, W, Huang, X, Gupta, A, Jang, WD, Wang, X, Arganda-Carreras, I, Lichtman, JW, Pfister, H Med Image Comput Comput Assist Interv 12265 : 66-76. doi: 10.1007/978-3-030-59722-1_7. PubMed PMID:33283212 PubMed Central PMC7713709
  • 2020 | Channel Embedding for Informative Protein Identification from Highly Multiplexed Images. Magid, SA, Jang, WD, Schapiro, D, Wei, D, Tompkin, J, Sorger, PK, Pfister, H Med Image Comput Comput Assist Interv 12265 : 3-13. doi: 10.1007/978-3-030-59722-1_1. PubMed PMID:33283211 PubMed Central PMC7713713
  • 2021 | Pharmacologic Screening Identifies Metabolic Vulnerabilities of CD8+ T Cells. Drijvers, JM, Gillis, JE, Muijlwijk, T, Nguyen, TH, Gaudiano, EF, Harris, IS, LaFleur, MW, Ringel, AE, Yao, CH, Kurmi, K, Juneja, VR, Trombley, JD, Haigis, MC, Sharpe, AH Cancer Immunol Res 9 (2): 184-199. doi: 10.1158/2326-6066.CIR-20-0384. PubMed PMID:33277233 PubMed Central PMC7864883
  • 2020 | VISTA: VIsual Semantic Tissue Analysis for pancreatic disease quantification in murine cohorts. Ternes, L, Huang, G, Lanciault, C, Thibault, G, Riggers, R, Gray, JW, Muschler, J, Chang, YH Sci Rep 10 (1): 20904. doi: 10.1038/s41598-020-78061-3. PubMed PMID:33262400 PubMed Central PMC7708430
  • 2021 | Myeloid-Derived Suppressor Cells Are a Major Source of Wnt5A in the Melanoma Microenvironment and Depend on Wnt5A for Full Suppressive Activity. Douglass, SM, Fane, ME, Sanseviero, E, Ecker, BL, Kugel, CH 3rd, Behera, R, Kumar, V, Tcyganov, EN, Yin, X, Liu, Q, Chhabra, Y, Alicea, GM, Kuruvilla, R, Gabrilovich, DI, Weeraratna, AT Cancer Res 81 (3): 658-670. doi: 10.1158/0008-5472.CAN-20-1238. PubMed PMID:33262126
  • 2021 | Clinical Efficacy and Molecular Response Correlates of the WEE1 Inhibitor Adavosertib Combined with Cisplatin in Patients with Metastatic Triple-Negative Breast Cancer. Keenan, TE, Li, T, Vallius, T, Guerriero, JL, Tayob, N, Kochupurakkal, B, Davis, J, Pastorello, R, Tahara, RK, Anderson, L, Conway, J, He, MX, Shannon, E, Godin, RE, Sorger, PK, D'Andrea, A, Overmoyer, B, Winer, EP, Mittendorf, EA, Van Allen, EM, Shapiro, GI, Tolaney, SM Clin Cancer Res 27 (4): 983-991. doi: 10.1158/1078-0432.CCR-20-3089. PubMed PMID:33257427 PubMed Central PMC7887044
  • 2020 | Head and neck squamous cell carcinoma. Johnson, DE, Burtness, B, Leemans, CR, Lui, VWY, Bauman, JE, Grandis, JR Nat Rev Dis Primers 6 (1): 92. doi: 10.1038/s41572-020-00224-3. PubMed PMID:33243986
  • 2020 | The gut microbiota is associated with immune cell dynamics in humans. Schluter, J, Peled, JU, Taylor, BP, Markey, KA, Smith, M, Taur, Y, Niehus, R, Staffas, A, Dai, A, Fontana, E, Amoretti, LA, Wright, RJ, Morjaria, S, Fenelus, M, Pessin, MS, Chao, NJ, Lew, M, Bohannon, L, Bush, A, Sung, AD, Hohl, TM, Perales, MA, van den Brink, MRM, Xavier, JB Nature 588 (7837): 303-307. doi: 10.1038/s41586-020-2971-8. PubMed PMID:33239790 PubMed Central PMC7725892
  • 2021 | Concurrent Dexamethasone Limits the Clinical Benefit of Immune Checkpoint Blockade in Glioblastoma. Iorgulescu, JB, Gokhale, PC, Speranza, MC, Eschle, BK, Poitras, MJ, Wilkens, MK, Soroko, KM, Chhoeu, C, Knott, A, Gao, Y, Lim-Fat, MJ, Baker, GJ, Bonal, DM, Nguyen, QD, Grant, GRL, Ligon, KL, Sorger, PK, Chiocca, EA, Anderson, AC, Kirschmeier, PT, Sharpe, AH, Freeman, GJ, Reardon, DA Clin Cancer Res 27 (1): 276-287. doi: 10.1158/1078-0432.CCR-20-2291. PubMed PMID:33239433
  • 2020 | Comparing the Efficacy of Cancer Therapies between Subgroups in Basket Trials. Palmer, AC, Plana, D, Sorger, PK Cell Syst 11 (5): 449-460.e2. doi: 10.1016/j.cels.2020.09.003. PubMed PMID:33220857
  • 2020 | Does placental invasiveness lead to higher rates of malignant transformation in mammals?: Response to: 'Available data suggests positive relationship between placental invasion an malignancy'. Boddy, AM, Abegglen, LM, Aktipis, A, Schiffman, JD, Maley, CC, Witte, C Evol Med Public Health 2020 (1): 215-216. doi: 10.1093/emph/eoaa025. PubMed PMID:33214902 PubMed Central PMC7658549
  • 2020 | Transmissible cancers and the evolution of sex under the Red Queen hypothesis. Aubier, TG, Galipaud, M, Erten, EY, Kokko, H PLoS Biol 18 (11): e3000916. doi: 10.1371/journal.pbio.3000916. PubMed PMID:33211684 PubMed Central PMC7676742
  • 2020 | Lifetime cancer prevalence and life history traits in mammals. Boddy, AM, Abegglen, LM, Pessier, AP, Aktipis, A, Schiffman, JD, Maley, CC, Witte, C Evol Med Public Health 2020 (1): 187-195. doi: 10.1093/emph/eoaa015. PubMed PMID:33209304 PubMed Central PMC7652303
  • 2020 | A Random Matrix Theory Approach to Denoise Single-Cell Data. Aparicio, L, Bordyuh, M, Blumberg, AJ, Rabadan, R Patterns (N Y) 1 (3): 100035. doi: 10.1016/j.patter.2020.100035. PubMed PMID:33205104 PubMed Central PMC7660363
  • 2020 | The MOBSTER R package for tumour subclonal deconvolution from bulk DNA whole-genome sequencing data. Caravagna, G, Sanguinetti, G, Graham, TA, Sottoriva, A BMC Bioinformatics 21 (1): 531. doi: 10.1186/s12859-020-03863-1. PubMed PMID:33203356 PubMed Central PMC7672894
  • 2021 | Immune Checkpoint Inhibitors for the Treatment of Cancer: Clinical Impact and Mechanisms of Response and Resistance. Bagchi, S, Yuan, R, Engleman, EG Annu Rev Pathol 16 : 223-249. doi: 10.1146/annurev-pathol-042020-042741. PubMed PMID:33197221
  • 2020 | High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue. Liu, Y, Yang, M, Deng, Y, Su, G, Enninful, A, Guo, CC, Tebaldi, T, Zhang, D, Kim, D, Bai, Z, Norris, E, Pan, A, Li, J, Xiao, Y, Halene, S, Fan, R Cell 183 (6): 1665-1681.e18. doi: 10.1016/j.cell.2020.10.026. PubMed PMID:33188776 PubMed Central PMC7736559
  • 2020 | Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA. Yuan, S, Peng, L, Park, JJ, Hu, Y, Devarkar, SC, Dong, MB, Shen, Q, Wu, S, Chen, S, Lomakin, IB, Xiong, Y Mol Cell 80 (6): 1055-1066.e6. doi: 10.1016/j.molcel.2020.10.034. PubMed PMID:33188728 PubMed Central PMC7833686
  • 2020 | Hyperprogression on immunotherapy with complete response to chemotherapy in a NSCLC patient with high PD-L1 and STK11: A case report. Fricke, J, Mambetsariev, I, Pharaon, R, Subbiah, S, Rajurkar, S, Salgia, R Medicine (Baltimore) 99 (46): e22323. doi: 10.1097/MD.0000000000022323. PubMed PMID:33181636 PubMed Central PMC7668523
  • 2020 | Turnover modulates the need for a cost of resistance in adaptive therapy. Strobl, MAR, West, J, Viossat, Y, Damaghi, M, Robertson-Tessi, M, Brown, JS, Gatenby, RA, Maini, PK, Anderson, ARA Cancer Res : . doi: 10.1158/0008-5472.CAN-20-0806. PubMed PMID:33172930
  • 2020 | The effects of age and systemic metabolism on anti-tumor T cell responses. Drijvers, JM, Sharpe, AH, Haigis, MC Elife 9 : . doi: 10.7554/eLife.62420. PubMed PMID:33170123 PubMed Central PMC7655106
  • 2020 | Chromatin regulatory genes differentially interact in networks to facilitate distinct GAL1 activity and noise profiles. Moreno, DF, Acar, M Curr Genet : . doi: 10.1007/s00294-020-01124-5. PubMed PMID:33159551
  • 2020 | Defining the Teratoma as a Model for Multi-lineage Human Development. McDonald, D, Wu, Y, Dailamy, A, Tat, J, Parekh, U, Zhao, D, Hu, M, Tipps, A, Zhang, K, Mali, P Cell 183 (5): 1402-1419.e18. doi: 10.1016/j.cell.2020.10.018. PubMed PMID:33152263 PubMed Central PMC7704916
  • 2020 | IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells. Lee, J, Robinson, ME, Ma, N, Artadji, D, Ahmed, MA, Xiao, G, Sadras, T, Deb, G, Winchester, J, Cosgun, KN, Geng, H, Chan, LN, Kume, K, Miettinen, TP, Zhang, Y, Nix, MA, Klemm, L, Chen, CW, Chen, J, Khairnar, V, Wiita, AP, Thomas-Tikhonenko, A, Farzan, M, Jung, JU, Weinstock, DM, Manalis, SR, Diamond, MS, Vaidehi, N, Müschen, M Nature 588 (7838): 491-497. doi: 10.1038/s41586-020-2884-6. PubMed PMID:33149299
  • 2020 | Rapid progression of disease from immunotherapy following targeted therapy: insights into treatment management and sequence. Pharaon, R, Mambetsariev, I, Fricke, J, Salgia, R J Thorac Dis 12 (9): 5096-5103. doi: 10.21037/jtd.2019.08.14. PubMed PMID:33145086 PubMed Central PMC7578509
  • 2020 | Role of immunotherapy and co-mutations on KRAS-mutant non-small cell lung cancer survival. Amanam, I, Mambetsariev, I, Gupta, R, Achuthan, S, Wang, Y, Pharaon, R, Massarelli, E, Koczywas, M, Reckamp, K, Salgia, R J Thorac Dis 12 (9): 5086-5095. doi: 10.21037/jtd.2020.04.18. PubMed PMID:33145085 PubMed Central PMC7578487
  • 2020 | Identifying the spatial and temporal dynamics of molecularly-distinct glioblastoma sub-populations. Morris, B, Curtin, L, Hawkins-Daarud, A, Hubbard, ME, Rahman, R, Smith, SJ, Auer, D, Tran, NL, Hu, LS, Eschbacher, JM, Smith, KA, Stokes, A, Swanson, KR, Owen, MR Math Biosci Eng 17 (5): 4905-4941. doi: 10.3934/mbe.2020267. PubMed PMID:33120534
  • 2020 | ACE2 localizes to the respiratory cilia and is not increased by ACE inhibitors or ARBs. Lee, IT, Nakayama, T, Wu, CT, Goltsev, Y, Jiang, S, Gall, PA, Liao, CK, Shih, LC, Schürch, CM, McIlwain, DR, Chu, P, Borchard, NA, Zarabanda, D, Dholakia, SS, Yang, A, Kim, D, Chen, H, Kanie, T, Lin, CD, Tsai, MH, Phillips, KM, Kim, R, Overdevest, JB, Tyler, MA, Yan, CH, Lin, CF, Lin, YT, Bau, DT, Tsay, GJ, Patel, ZM, Tsou, YA, Tzankov, A, Matter, MS, Tai, CJ, Yeh, TH, Hwang, PH, Nolan, GP, Nayak, JV, Jackson, PK Nat Commun 11 (1): 5453. doi: 10.1038/s41467-020-19145-6. PubMed PMID:33116139 PubMed Central PMC7595232
  • 2020 | Epigenetic Mechanisms Contribute to Evolutionary Adaptation of Gene Network Activity under Environmental Selection. Luo, X, Song, R, Moreno, DF, Ryu, HY, Hochstrasser, M, Acar, M Cell Rep 33 (4): 108306. doi: 10.1016/j.celrep.2020.108306. PubMed PMID:33113358 PubMed Central PMC7656290
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  • 2020 | Pathway-Specific Genome Editing of PI3K/mTOR Tumor Suppressor Genes Reveals that PTEN Loss Contributes to Cetuximab Resistance in Head and Neck Cancer. Izumi, H, Wang, Z, Goto, Y, Ando, T, Wu, X, Zhang, X, Li, H, Johnson, DE, Grandis, JR, Gutkind, JS Mol Cancer Ther 19 (7): 1562-1571. doi: 10.1158/1535-7163.MCT-19-1036. PubMed PMID:32430488 PubMed Central PMC7357849
  • 2020 | A Single-Cell Transcriptional Roadmap of the Mouse and Human Lymph Node Lymphatic Vasculature. Xiang, M, Grosso, RA, Takeda, A, Pan, J, Bekkhus, T, Brulois, K, Dermadi, D, Nordling, S, Vanlandewijck, M, Jalkanen, S, Ulvmar, MH, Butcher, EC Front Cardiovasc Med 7 : 52. doi: 10.3389/fcvm.2020.00052. PubMed PMID:32426372 PubMed Central PMC7204639
  • 2020 | Enhancer reprogramming driven by high-order assemblies of transcription factors promotes phenotypic plasticity and breast cancer endocrine resistance. Bi, M, Zhang, Z, Jiang, YZ, Xue, P, Wang, H, Lai, Z, Fu, X, De Angelis, C, Gong, Y, Gao, Z, Ruan, J, Jin, VX, Marangoni, E, Montaudon, E, Glass, CK, Li, W, Huang, TH, Shao, ZM, Schiff, R, Chen, L, Liu, Z Nat Cell Biol 22 (6): 701-715. doi: 10.1038/s41556-020-0514-z. PubMed PMID:32424275 PubMed Central PMC7737911
  • 2020 | The Evolution of Human Cancer Gene Duplications across Mammals. Tollis, M, Schneider-Utaka, AK, Maley, CC Mol Biol Evol 37 (10): 2875-2886. doi: 10.1093/molbev/msaa125. PubMed PMID:32421773 PubMed Central PMC7530603
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  • 2020 | Reciprocal fine-tuning of progesterone and prolactin-regulated gene expression in breast cancer cells. Holloran, SM, Nosirov, B, Walter, KR, Trinca, GM, Lai, Z, Jin, VX, Hagan, CR Mol Cell Endocrinol 511 : 110859. doi: 10.1016/j.mce.2020.110859. PubMed PMID:32407979
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  • 2020 | Pooled CRISPR screens with imaging on microraft arrays reveals stress granule-regulatory factors. Wheeler, EC, Vu, AQ, Einstein, JM, DiSalvo, M, Ahmed, N, Van Nostrand, EL, Shishkin, AA, Jin, W, Allbritton, NL, Yeo, GW Nat Methods 17 (6): 636-642. doi: 10.1038/s41592-020-0826-8. PubMed PMID:32393832 PubMed Central PMC7357298
  • 2020 | Multi-omic single-cell snapshots reveal multiple independent trajectories to drug tolerance in a melanoma cell line. Su, Y, Ko, ME, Cheng, H, Zhu, R, Xue, M, Wang, J, Lee, JW, Frankiw, L, Xu, A, Wong, S, Robert, L, Takata, K, Yuan, D, Lu, Y, Huang, S, Ribas, A, Levine, R, Nolan, GP, Wei, W, Plevritis, SK, Li, G, Baltimore, D, Heath, JR Nat Commun 11 (1): 2345. doi: 10.1038/s41467-020-15956-9. PubMed PMID:32393797 PubMed Central PMC7214418
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